An application has been made to the FDA for apalutamide, a possible hormonal treatment for men who are castrate resistant, but not yet metastatic.
On the horizon, a new Zytiga formulation. It's smaller and more active than the current Zytiga. It will be much easier to swallow.
Retreatment with cabazitaxel (Jevtana) might be an effective option for you if you have burned through all the other FDA approved treatments for advanced prostate cancer.
Using Niclosamide (FDA approved) and Bicalutamide (Casodex) in Combination Overcomes Enzalutamide (Xtandi) and Bicalutamide Resistant Prostate Cancer.
For men who have aggressive advanced prostate cancer and have "burned through' many other treatments an investigation radiotherapy treatment called LU-177 holds the potential for extending their life and improving its quality.