Bipolar Hormone Therapy, BAT for Prostate Cancer, BAT Patient Guide
Cancer ABCs
Bipolar Androgen Therapy (BAT): A Patient's ...

This complete guide to Bipolar Androgen Therapy (BAT) should be your stepping-off point if you are interested in using BAT to treat your castrate-resistant prostate cancer (CrPC).

Bipolar Androgen Therapy (BAT): A Patient's Guide
Radiopharmaceutical Treat
Cancer ABCs
Which is Better, 177Lu-PSMA-617 (Pluvicto) or ...

Several men have asked us if they are better off having 177Lu-PSMA-617 (Pluvicto) or Xofigo, a radiopharmaceutical drug that treats bone metastases. There is no simple answer, and the answer is not the same for each of us. Making a sound decision can be helped by understanding the mode of action and the limits of each treatment.

Which is Better, 177Lu-PSMA-617 (Pluvicto) or Xofigo (Radium-223)
PARP Inhibitors, Companion Diagnostics, BRACA
Cancer ABCs
Understanding the PARP Inhibitors - Who Will ...

LYNPARZA (olaparib) and RUBRACA (rucaparib) are PARP Inhibitors that were FDA approved in May of 2020 for men with castrate resistant prostate cancer who also have certain genetic mutations. The FDA also approved certain Companion Diagnostic genetic tests to go along with the decision making to use these PARP Inhibitors.

There is a lot of information now available with these recent developments which makes decision making confusing.

Understanding the PARP Inhibitors - Who Will Benefit?
Radiation Side Effect Man, Managing Radiation Side
Cancer ABCs
Managing Late Stage Radiation Side Effects

There are several possible side effects that can result from receiving radiation treatment. The most common of these side effects include the development of scar tissue that makes it hard to urinate (pee), defecate (poop), and in some instances, link the activity of either peeing and pooping together; bladder or colon bleeding and diarrhea. 

Managing Late Stage Radiation Side Effects

2nd Line Hormone Therapy

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177Lu-PSMA-617 Theranostics Might Be More Active and Safer than Cabazitaxel 

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177Lu-PSMA-617 Theranostics Might Be More Active and Safer than Cabazitaxel 

The trial showed that the LuPSMA treatment delayed prostate cancer progression versus Jevtana, with a comparable benefit observed in radiographic progression-free survival and PSA progression-free survival.

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Optimal Chemo-Hormonal Sequencing for mCRPC Maybe Taxotere – Zytiga – Jevtana – Xtandi 

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Optimal Chemo-Hormonal Sequencing for mCRPC Maybe Taxotere – Zytiga – Jevtana – Xtandi 

Optimal Chemo-Hormonal Sequencing for metastatic castrate resistant prostate cancer (mCRPC) maybe Taxotere – Zytiga – Jevtana – Xtandi

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Is ADT Necessary When You Take Abiraterone Acetate (Zytiga)?

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Is ADT Necessary When You Take Abiraterone Acetate (Zytiga)?

The researchers concluded that ADT may not be necessary for men receiving Zytiga and prednisone; however, some men may experience a rapid increase of serum testosterone levels, warranting close monitoring and adding back ADT.

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Understanding the Recent Advances in Treating Castrate Sensitive Prostate Cancer 

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Understanding the Recent Advances in Treating Castrate Sensitive Prostate Cancer 

Abiraterone, enzalutamide, apalutamide, and docetaxel could be considered for this patient population (castrate sensitive prostate cancer patients), noted Taplin. "None of us can [confirm] that one [option] is better than the other; [the treatment decision] needs to be individualized [by weighing the] pros and cons [with each agent] for each patient," Taplin concluded.

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Apalutamide (Erleada® ) Approved for Metastatic Castrate Sensitive Prostate Cancer

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The Food and Drug Administration (FDA) approved apalutamide (ERLEADA), for men with metastatic castration-sensitive prostate cancer (mCSPC).

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The Synergy between Xtandi and Zytiga with ADT – Is it Important to Continue Taking ADT Along with Xtandi and Zytiga?

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Why are Zytiga and Xtandi added to ADT and not substituted for ADT? Do I really need to continue ADT when I use Xtandi or Zytiga?

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