68Ga-PSMA

Stereotactic Body Radiotherapy (SBRT) for Oligometastatic Prostate Cancer Recurrence: A Meta-Analysis - Positive Notes

Stereotactic Body Radiotherapy (SBRT) for Oligometastatic Prostate Cancer Recurrence: A Meta-Analysis - Positive Notes

A meta-analysis was performed to evaluate the treatment efficacy of stereotactic body radiotherapy (SBRT) in men with oligometastatic prostate cancer recurrence and to assess whether there is any relationship between biologically effective dose (BED) (how much radiation to use) and local control (LC) (the success of the radiation treatment in controlling the existing metastases as well as the development of new local metastases).  

Assessing the Under-Estimation of Nodal Tumor Burden by using 68GA PSMA and 11C-Choline PET/CT Scan

The technology, PET/CT exemplifies one of the most sensitive of the diagnostic modalities we have to assess the spread of recurrent prostate cancer. 

However, there is an assumption that even PET/CT, despite its sensitivity, still under-estimates the actual tumor burden. There is an additional hypothesis that the under estimation of tumor burden increases progressively by the number of positive nodes that are visualized by preoperative imaging.