The opinion of two Professionals in the know, - Gleason 9 and Gleason 10 prostate cancer is best treated by multiple modalities; surgery, radiation and hormone therapy used in combination.
Transitioning from Degarelix to Lupron can cause a dangerous PSA flare that needs to be avoided by adding an anti-androgen drug like Casodex prior to making the transition; not unlike when Lupron is started as an initial treatment.
Zytiga And Prednisone Provide Significant Benefits Beyond Survival With Newly Diagnosed Metastatic Hormone-Sensitive and Castration-Resistant Prostate Cancer
The current standard of care for men with non-metastatic prostate cancer who are on hormone therapy (ADT) does not include the use of any of the bisphosphonate drugs. Some men might benefit by using them at this stage.